Pregabalina, Lyrica


Pregabalina / Pregabalin

Fármacos anticonvulsivantes ||

Informacion pregabalina en wikimecum

Ficha Técnica de la EMEA ) Lyrica) ||

Encuesta pacientes o personas interesadas


Pregabalina en trastorno de ansiedad generalizada (nueva indicación)

Bibliografía en Castellano



Analisis coste-efectividad del tratamiento de la epilepsia parcial refractaria: un modelo de simulacion de pregabalina y levetiracetam.
Revista de neurologia. 2007 Oct 16-31; 45(8): 460-7. Diaz, S; Argumosa, A; Horga de la Parte, J F; Vera-Llonch, M; Dukes, E; Rejas-Gutierrez, J;

Nuevos blancos moleculares en el tratamiento farmacologico de los trastornos de ansiedad.
Vertex (Buenos Aires, Argentina). 2004; 15 Suppl 15-11. Barenbaum, Ruben D; Rilla Manta, Luis;

Experiencia clinica de la pregabalina en el tratamiento de las epilepsias focales.
Revista de neurologia. 2005 May 16-31; 40(10): 609-13. Gil-Nagel Rein, A; Gomez-Alonso, J;

Ictericia asociada al tratamiento con pregabalina.
Medicina clinica. 2008 Sep 27; 131(10): 398; author reply 39. Orive Calzada, Aitor; Alvarez Rubio, Manuel; Romero Izquierdo, Sonia; Erana Ledesma, Luis;

Colestasis asociada a tratamiento con pregabalina.
Medicina clinica. 2008 Feb 9; 130(4): 157-8. Crespo Perez, Laura; Moreira Vicente, Victor; Manzano Fernandez, Rebeca; Garcia Aguilera, Xavier Arturo;

Pregabalina. Aportaciones de los ligandos alpha2delta de canales de calcio en el tratamiento de la epilepsia y el dolor neuropatico.
Revista de neurologia. 2006 Feb 16-28; 42(4): 223-37. Horga de la Parte, J F; Horga, A;

Pregabalina. Un nuevo tratamiento para el dolor neuropatico.
Neurologia (Barcelona, Spain). 2006 Mar; 21(2): 96-103. Lopez-Trigo, J; Sancho Rieger, J;

Otras opciones terapeuticas en la fibromialgia.
Medicina clinica. 2006 Jun 10; 127(2): 76-7. Callejas-Rubio, Jose L; Lopez-Perez, Lourdes; Navarro-Pelayo, Francisco; Ortego-Centeno, Norberto;

Toxicidad por pregabalina en una paciente en hemodialisis cronica.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia. 2007; 27(2): 236. Homs, M; Bonal, J; Canas, L; Romero, R;


Bibliografía en Core Clinical Journals



Bad medicine: gabapentin and pregabalin.
BMJ (Clinical research ed.). 2013; 347f6747. Spence, Des;

The analgesic efficiency of combined pregabalin and ketamine for total hip arthroplasty: a randomised, double-blind, controlled study.
Anaesthesia. 2014 Jan; 69(1): 46-52. Martinez, V; Cymerman, A; Ben Ammar, S; Fiaud, J F; Rapon, C; Poindessous, F; Judet, T; Chauvin, M; Bouhassira, D; Sessler, D; Mazoit, X; Fletcher, D;

Comparison of pregabalin with pramipexole for restless legs syndrome.
The New England journal of medicine. 2014 Feb 13; 370(7): 621-31. Allen, Richard P; Chen, Crystal; Garcia-Borreguero, Diego; Polo, Olli; Dubrava, Sarah; Miceli, Jeffrey; Knapp, Lloyd; Winkelman, John W;

A randomized trial of pregabalin in patients with neuropathic pain due to spinal cord injury.
Neurology. 2013 Feb 5; 80(6): 533-9. Cardenas, Diana D; Nieshoff, Edward C; Suda, Kota; Goto, Shin-Ichi; Sanin, Luis; Kaneko, Takehiko; Sporn, Jonathan; Parsons, Bruce; Soulsby, Matt; Yang, Ruoyong; Whalen, Ed; Scavone, Joseph M; Suzuki, Makoto M; Knapp, Lloyd E;

Characterization of a new animal model for evaluation and treatment of back pain due to lumbar facet joint osteoarthritis.
Arthritis and rheumatism. 2011 Oct; 63(10): 2966-73. Kim, Jae-Sung; Kroin, Jeffrey S; Buvanendran, Asokumar; Li, Xin; van Wijnen, Andre J; Tuman, Kenneth J; Im, Hee-Jeong;

"Seeing" how our drugs work brings translational added value.
Anesthesiology. 2013 Dec; 119(6): 1247-8. Tracey, Irene;

The immunomodulatory effect of pregabalin on spleen cells in neuropathic mice.
Anesthesia and analgesia. 2012 Oct; 115(4): 830-6. Jang, Yeon; Song, Ho-Kyung; Yeom, Mi Young; Jeong, Dae Chul;

A double-blind randomized crossover study to evaluate the timing of pregabalin for third molar surgery under local anesthesia.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. 2012 Jan; 70(1): 25-30. Cheung, Chi Wai; Choi, Wing Shan; Leung, Yiu Yan; Lui, Frances; Ng, Jacobus Kwok Fu; Hei-Ho, Anthony Ming; Irwin, Michael Garnet;

Cerebrospinal fluid neurotransmitter changes during the perioperative period in patients undergoing total knee replacement: a randomized trial.
Anesthesia and analgesia. 2012 Feb; 114(2): 434-41. Buvanendran, Asokumar; Kroin, Jeffrey S; Della Valle, Craig J; Moric, Mario; Tuman, Kenneth J;

Peripheral edema with pregabalin.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. 2013 Jul 9; 185(10): E506. Gallagher, Romayne; Apostle, Nicole;

Perioperative gabapentinoids: choice of agent, dose, timing, and effects on chronic postsurgical pain.
Anesthesiology. 2013 Nov; 119(5): 1215-21. Schmidt, Peter C; Ruchelli, Gabriela; Mackey, Sean C; Carroll, Ian R;

Pregabalin monotherapy in patients with partial-onset seizures: a historical-controlled trial.
Neurology. 2014 Feb 18;82(7):590-7. doi: 10.1212/WNL.0000000000000119. Epub 2014 Jan 10. French J., Kwan P., Fakhoury T., Pitman V., DuBrava S., Knapp L., Yurkewicz L.

Chronic postsurgical pain: are we closer to understanding the puzzle?
Anesthesia and analgesia. 2012 Aug; 115(2): 231-2. Buvanendran, Asokumar;

The efficacy of morphine, pregabalin, gabapentin, and duloxetine on mechanical allodynia is different from that on neuroma pain in the rat neuropathic pain model.
Anesthesia and analgesia. 2012 Jul; 115(1): 182-8. Miyazaki, Rika; Yamamoto, Tatsuo;

Review of current guidelines on the care of postherpetic neuralgia.
Postgraduate medicine. 2011 Sep; 123(5): 134-42. Argoff, Charles E;

Drugs for neuropathic pain.
BMJ (Clinical research ed.). 2013; 347f7339. Kalso, Eija; Aldington, D J; Moore, R A;

Pregabalin rectifies aberrant brain chemistry, connectivity, and functional response in chronic pain patients.
Anesthesiology. 2013 Dec; 119(6): 1453-64. Harris, Richard E; Napadow, Vitaly; Huggins, John P; Pauer, Lynne; Kim, Jieun; Hampson, Johnson; Sundgren, Pia C; Foerster, Bradley; Petrou, Myria; Schmidt-Wilcke, Tobias; Clauw, Daniel J;

Therapeutic dilemma for restless legs syndrome.
N Engl J Med. 2014 Feb 13;370(7):667-8. doi: 10.1056/NEJMe1313155. Chokroverty S.

Evidence-based guidance for the management of postherpetic neuralgia in primary care.
Postgraduate medicine. 2013 Jul; 125(4): 191-202. Harden, R Norman; Kaye, Alan David; Kintanar, Thomas; Argoff, Charles E;

The prevention of chronic postsurgical pain using gabapentin and pregabalin: a combined systematic review and meta-analysis.
Anesthesia and analgesia. 2012 Aug; 115(2): 428-42. Clarke, Hance; Bonin, Robert P; Orser, Beverley A; Englesakis, Marina; Wijeysundera, Duminda N; Katz, Joel;



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